As cannabis vaping continues to rise in popularity, vape cartridge options are evolving with both flavor and effect in mind. In 2025, customers are not only seeking high potency but also well-rounded terpene profiles and consistent quality—especially when ordering through delivery platforms. Among hundreds of available products, a handful of strains have emerged as clear customer favorites across legal cannabis markets.

Here’s a look at the top five most popular vape cartridge strains and flavors customers are ordering for delivery in 2025:

1. Wedding Cake (Hybrid)

Wedding Cake continues to dominate the vape cartridge scene. Known for its rich vanilla and earthy flavor profile, this hybrid strain offers a powerful yet balanced high. Users often report a relaxed body effect paired with mental clarity, making it a versatile option for both evening and creative daytime use. Its popularity also stems from its consistent performance, no matter the brand offering the cartridge.

2. Blue Dream (Sativa-Dominant Hybrid)

Blue Dream remains a staple in vape menus nationwide. The sweet, berry-like flavor and uplifting effects make it ideal for daytime use. Its ability to deliver a calming body buzz without heavy sedation appeals to novice and veteran users alike. In 2025, Blue Dream’s popularity is supported by its adaptability—it’s available in live resin, distillate, and rosin formats, depending on consumer preference.

3. Gelato 33 (Hybrid)

Gelato 33 stands out for its sweet, creamy taste and relaxing but focused effects. Vapers love its ability to enhance mood while keeping them functional. Whether it’s used socially or as a stress-reliever after a long day, Gelato 33 checks all the boxes for flavor, potency, and smoothness. Its dense clouds and satisfying pull make it a go-to in both 0.5g and 1g cartridge formats.

4. Zkittlez (Indica-Dominant Hybrid)

Zkittlez continues its run as a top contender among flavor-chasers. Its fruity, candy-like aroma and mellow high make it perfect for winding down without full couch lock. The indica-dominant genetics offer stress and anxiety relief, while still allowing for light conversation or relaxing entertainment. It’s especially popular among consumers seeking tasty cartridges that don’t sacrifice effect.

5. Sour Diesel (Sativa)

For those who prefer a more energizing experience, Sour Diesel remains a best-seller. With its pungent aroma and fast-acting cerebral effects, it’s a go-to vape for daytime productivity and creative projects. In 2025, Sour Diesel is experiencing a resurgence as more consumers look for vape cartridges that enhance motivation and focus without over-stimulation.

These five vape cartridge strains offer something for everyone—whether the goal is to unwind, stay productive, or enjoy a flavorful session. Delivery services are increasingly stocking these fan favorites to meet ongoing demand. With the right combination of terpenes, potency, and reliability, these strains have secured their place at the top of the vape cartridge charts for 2025.